The subjective response to treatment was correlated with changes in gait parameters. Single–limb support time, velocity, fatigability, and swing phase were not improved. Only double–limb support time was found to be significantly different. The remaining gait variables were not changed. Separately, the subset of patients that achieved greater than 70% subjective pain relief had no objective improvements in gait parameters. Hyaluronic acid therapy may result in a placebo effect for the treatment of gonarthrosis.
Journal of Arthroplasty, 12/22/09
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